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Gene Editing in Human Pluripotent Stem Cells: Choosing the Correct Path

The recent emergence of targeted nucleases has opened up new opportunities for performing genetic modifications with human pluripotent stem cells (hPSCs). These modifications can range from the creation of a routine knock-out to the more challenging single point-mutation. For both the new and establ...

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Detalhes bibliográficos
Publicado no:J Stem Cell Regen Biol
Main Authors: Singh, Amar M., Adjan Steffey, Valeriya V., Yeshi, Tseten, Allison, Daniel W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686154/
https://ncbi.nlm.nih.gov/pubmed/26702451
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