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Significant Differences in Cell-Cell Fusion and Viral Entry Between Strains Revealed By Scanning Mutagenesis of The C-Heptad Repeat of HIV GP41
The transmembrane subunit, gp41, of HIV envelope mediates the viral fusion step of entry into the host cell. The protein consists of an extracellular domain, a transmembrane domain, and a cytoplasmic tail. The extracellular domain contains a fusion peptide, an N-terminal heptad repeat (NHR), a loop...
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| Veröffentlicht in: | Biochemistry |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4686141/ https://ncbi.nlm.nih.gov/pubmed/23621782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400201h |
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