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Molecular and biological changes in the cold-adapted "master strain" A/AA/6/60 (H2N2) influenza virus.

The live cold-adapted (ca) A/AA/6/60 influenza vaccine is being commercially developed for worldwide use in children and is being used as a model for other live vaccines. Although it has been proven safe and immunogenic, the molecular basis of cold adaptation has never been determined. To identify s...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Herlocher, M L, Maassab, H F, Webster, R G
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1993
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46861/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8327480/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.13.6032
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