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Triptolide reverses the Taxol resistance of lung adenocarcinoma by inhibiting the NF-κB signaling pathway and the expression of NF-κB-regulated drug-resistant genes

Paclitaxel (or Taxol(®)) is a first-line chemotherapeutic drug for the treatment of non-small cell lung cancer; however, resistance to the drug is an important factor, which influences the outcome of chemotherapy. The present study aimed to investigate the role of triptolide (TPL) in reversing Taxol...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Principais autores: JIANG, NING, DONG, XIAO-PENG, ZHANG, SUO-LIN, YOU, QING-YONG, JIANG, XING-TAO, ZHAO, XIAO-GANG
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686042/
https://ncbi.nlm.nih.gov/pubmed/26531258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2015.4493
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