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A simple mechanistic explanation for original antigenic sin and its alleviation by adjuvants

A large number of published studies have shown that adaptive immunity to a particular antigen, including pathogen-derived, can be boosted by another, cross-reacting antigen while inducing suboptimal immunity to the latter. Although this phenomenon, called original antigenic sin (OAS), was first repo...

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Detalhes bibliográficos
Publicado no:J R Soc Interface
Autor principal: Ndifon, Wilfred
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4685838/
https://ncbi.nlm.nih.gov/pubmed/26577593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2015.0627
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