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A novel and practical asymmetric synthesis of dapoxetine hydrochloride
A novel and practical asymmetric synthesis of dapoxetine hydrochloride by using the chiral auxiliary (S)-tert-butanesulfinamide was explored. The synthesis was concise, mild, and easy to perform. The overall yield and stereoselectivity were excellent.
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| Udgivet i: | Beilstein J Org Chem |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Beilstein-Institut
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4685759/ https://ncbi.nlm.nih.gov/pubmed/26734109 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.11.283 |
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