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Insights into Hydrate Formation and Stability of Morphinanes from a Combination of Experimental and Computational Approaches

[Image: see text] Morphine, codeine, and ethylmorphine are important drug compounds whose free bases and hydrochloride salts form stable hydrates. These compounds were used to systematically investigate the influence of the type of functional groups, the role of water molecules, and the Cl(–) counte...

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Xehetasun bibliografikoak
Argitaratua izan da:Mol Pharm
Egile Nagusiak: Braun, Doris E., Gelbrich, Thomas, Kahlenberg, Volker, Griesser, Ulrich J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Chemical Society 2014
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4685752/
https://ncbi.nlm.nih.gov/pubmed/25036525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp500334z
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