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Insights into Hydrate Formation and Stability of Morphinanes from a Combination of Experimental and Computational Approaches
[Image: see text] Morphine, codeine, and ethylmorphine are important drug compounds whose free bases and hydrochloride salts form stable hydrates. These compounds were used to systematically investigate the influence of the type of functional groups, the role of water molecules, and the Cl(–) counte...
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| Publicado no: | Mol Pharm |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2014
|
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4685752/ https://ncbi.nlm.nih.gov/pubmed/25036525 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp500334z |
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