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Structural determinants of reductive terpene cyclization in iridoid biosynthesis
The carbon skeleton of ecologically and pharmacologically important iridoid monoterpenes is formed in a reductive cyclization reaction unrelated to canonical terpene cyclization. Here we report the crystal structure of the recently discovered iridoid cyclase (Catharanthus roseus) bound to a mechanis...
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| Gepubliceerd in: | Nat Chem Biol |
|---|---|
| Hoofdauteurs: | , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4685742/ https://ncbi.nlm.nih.gov/pubmed/26551396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1955 |
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