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Profibrotic Role for Interleukin-4 in Cardiac Remodeling and Dysfunction

Elevated interleukin-4 (IL-4) levels are associated with cardiac fibrosis in hypertension and heart failure in both patients and experimental animals. We hypothesized that chronically elevated IL-4 induces cardiac fibrosis, resulting in a predisposition of the heart to angiotensin II–induced damage....

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Detaylı Bibliyografya
Yayımlandı:Hypertension
Asıl Yazarlar: Peng, Hongmei, Sarwar, Zeyd, Yang, Xiao-Ping, Peterson, Edward L., Xu, Jiang, Janic, Branislava, Rhaleb, Nadia, Carretero, Oscar A., Rhaleb, Nour-Eddine
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4685692/
https://ncbi.nlm.nih.gov/pubmed/26195478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.115.05627
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