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Huntington’s Disease: Can Mice Lead the Way to Treatment?

Mouse models for Huntington’s Disease and HD patients demonstrate motor and behavioral dysfunctions, such as progressive loss of coordination and memory, and share similar transcriptional profiles and striatal neuron atrophy. Clear differences between the mouse and human diseases include almost comp...

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Detaylı Bibliyografya
Yayımlandı:Neuron
Asıl Yazarlar: Crook, Zachary R., Housman, David
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4685469/
https://ncbi.nlm.nih.gov/pubmed/21315254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2010.12.035
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