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Huntington’s Disease: Can Mice Lead the Way to Treatment?

Mouse models for Huntington’s Disease and HD patients demonstrate motor and behavioral dysfunctions, such as progressive loss of coordination and memory, and share similar transcriptional profiles and striatal neuron atrophy. Clear differences between the mouse and human diseases include almost comp...

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Bibliografski detalji
Izdano u:Neuron
Glavni autori: Crook, Zachary R., Housman, David
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4685469/
https://ncbi.nlm.nih.gov/pubmed/21315254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2010.12.035
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