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Huntington’s Disease: Can Mice Lead the Way to Treatment?

Mouse models for Huntington’s Disease and HD patients demonstrate motor and behavioral dysfunctions, such as progressive loss of coordination and memory, and share similar transcriptional profiles and striatal neuron atrophy. Clear differences between the mouse and human diseases include almost comp...

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Detalles Bibliográficos
Publicado en:Neuron
Main Authors: Crook, Zachary R., Housman, David
Formato: Artigo
Idioma:Inglês
Publicado: 2011
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4685469/
https://ncbi.nlm.nih.gov/pubmed/21315254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2010.12.035
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