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Dysregulation of dopamine receptor D2 as a sensitive measure for Huntington disease pathology in model mice

The ability to quantitatively evaluate the impact of a potential therapeutic intervention for Huntington disease (HD) in animal models for the disease is a critical step in the pathway to development of an effective therapy for this devastating neurodegenerative disorder. We report here an approach...

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Detalhes bibliográficos
Main Authors: Crook, Zachary R., Housman, David E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358846/
https://ncbi.nlm.nih.gov/pubmed/22529362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1204542109
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