Microvesicle phenotypes are associated with transfusion requirements and mortality in subjects with severe injuries

BACKGROUND: Severe injury often results in substantial bleeding and mortality. Injury provokes cellular activation and release of extracellular vesicles. Circulating microvesicles (MVs) are predominantly platelet-derived and highly procoagulant. They support hemostasis and vascular function. The rol...

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Bibliografiske detaljer
Udgivet i:J Extracell Vesicles
Main Authors: Matijevic, Nena, Wang, Yao-Wei W., Holcomb, John B., Kozar, Rosemary, Cardenas, Jessica C., Wade, Charles E.
Format: Artigo
Sprog:Inglês
Udgivet: Co-Action Publishing 2015
Fag:
Original Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4685295/
https://ncbi.nlm.nih.gov/pubmed/26689982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3402/jev.v4.29338
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