Cellular microparticle and thrombogram phenotypes in the Prospective Observational Multicenter Major Trauma Transfusion (PROMMTT) Study: correlation with coagulopathy

BACKGROUND: Trauma-induced coagulopathy following severe injury is associated with increased bleeding and mortality. Injury may result in alteration of cellular phenotypes and release of cell-derived microparticles (MP). Circulating MPs are procoagulant and support thrombin generation (TG) and clott...

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Main Authors: Matijevic, Nena, Wang, Yao-Wei W., Wade, Charles E., Holcomb, John B., Cotton, Bryan A., Schreiber, Martin A., Muskat, Peter, Fox, Erin E., del Junco, Deborah J., Cardenas, Jessica C., Rahbar, Mohammad H., Cohen, Mitchell Jay
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4160305/
https://ncbi.nlm.nih.gov/pubmed/25086657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.thromres.2014.07.023
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