Cellular microparticle and thrombogram phenotypes in the Prospective Observational Multicenter Major Trauma Transfusion (PROMMTT) Study: correlation with coagulopathy

BACKGROUND: Trauma-induced coagulopathy following severe injury is associated with increased bleeding and mortality. Injury may result in alteration of cellular phenotypes and release of cell-derived microparticles (MP). Circulating MPs are procoagulant and support thrombin generation (TG) and clott...

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Main Authors: Matijevic, Nena, Wang, Yao-Wei W., Wade, Charles E., Holcomb, John B., Cotton, Bryan A., Schreiber, Martin A., Muskat, Peter, Fox, Erin E., del Junco, Deborah J., Cardenas, Jessica C., Rahbar, Mohammad H., Cohen, Mitchell Jay
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4160305/
https://ncbi.nlm.nih.gov/pubmed/25086657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.thromres.2014.07.023
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