Finding of a highly efficient ZFN pair for Aqpep gene functioning in murine zygotes

The generation efficiencies of mutation-induced mice when using engineered zinc-finger nucleases (ZFNs) have been generally 10 to 20% of obtained pups in previous studies. The discovery of high-affinity DNA-binding modules can contribute to the generation of various kinds of novel artificial chromat...

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Vydáno v:J Reprod Dev
Hlavní autoři: FUJII, Wataru, ONUMA, Asuka, YOSHIOKA, Shin, NAGASHIMA, Keisuke, SUGIURA, Koji, NAITO, Kunihiko
Médium: Artigo
Jazyk:Inglês
Vydáno: The Society for Reproduction and Development 2015
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4685226/
https://ncbi.nlm.nih.gov/pubmed/26460691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1262/jrd.2015-087
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