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Finding of a highly efficient ZFN pair for Aqpep gene functioning in murine zygotes
The generation efficiencies of mutation-induced mice when using engineered zinc-finger nucleases (ZFNs) have been generally 10 to 20% of obtained pups in previous studies. The discovery of high-affinity DNA-binding modules can contribute to the generation of various kinds of novel artificial chromat...
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| Publicado no: | J Reprod Dev |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Society for Reproduction and Development
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4685226/ https://ncbi.nlm.nih.gov/pubmed/26460691 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1262/jrd.2015-087 |
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