B Cells Are Multifunctional Players in Multiple Sclerosis Pathogenesis: Insights from Therapeutic Interventions

Multiple sclerosis (MS) is a severe disease of the central nervous system (CNS) characterized by autoimmune inflammation and neurodegeneration. Historically, damage to the CNS was thought to be mediated predominantly by activated pro-inflammatory T cells. B cell involvement in the pathogenesis of MS...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Claes, Nele, Fraussen, Judith, Stinissen, Piet, Hupperts, Raymond, Somers, Veerle
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2015
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4685142/
https://ncbi.nlm.nih.gov/pubmed/26734009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00642
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