Synthesis, Antiviral Activity and Resistance of a Novel Small Molecule HIV-1 Entry Inhibitor

One of the most critical requirements of the infection of the human immunodeficiency virus type 1 (HIV-1) is the interaction of its surface envelope glycoprotein gp120 with the cellular receptor CD4, which initiates virus entry to cells. Therefore, envelope glycoprotein gp120 has been validated as a...

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Bibliographic Details
Published in:Bioorg Med Chem
Main Authors: Curreli, Francesca, Haque, Kashfia, Xie, Lihua, Qiu, Qian, Xu, Jinfeng, Yong, Weizhong, Tong, Xiaohe, Debnath, Asim K.
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684972/
https://ncbi.nlm.nih.gov/pubmed/26602829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2015.11.006
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