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Association of Sphingosine‐1‐phosphate (S1P)/S1P Receptor‐1 Pathway with Cell Proliferation and Survival in Canine Hemangiosarcoma

BACKGROUND: Sphingosine‐1‐phosphate (S1P) is a key biolipid signaling molecule that regulates cell growth and survival, but it has not been studied in tumors from dogs. HYPOTHESIS/OBJECTIVES: S1P/S1P(1) signaling will contribute to the progression of hemangiosarcoma (HSA). ANIMALS: Thirteen spontane...

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Detalhes bibliográficos
Publicado no:J Vet Intern Med
Main Authors: Rodriguez, A.M., Graef, A.J., LeVine, D.N., Cohen, I.R., Modiano, J.F., Kim, J.‐H.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684944/
https://ncbi.nlm.nih.gov/pubmed/26118793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jvim.13570
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