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Recent advances and new strategies in targeting Plk1 for anticancer therapy
Polo-like kinase 1 (Plk1) plays key roles in regulating mitotic processes that are critical for cellular proliferation. Overexpression of Plk1 is tightly associated with the development of certain cancers in humans, and a large body of evidence suggests that Plk1 is an attractive target for anticanc...
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Publicado no: | Trends Pharmacol Sci |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4684765/ https://ncbi.nlm.nih.gov/pubmed/26478211 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2015.08.013 |
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