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Recent advances and new strategies in targeting Plk1 for anticancer therapy

Polo-like kinase 1 (Plk1) plays key roles in regulating mitotic processes that are critical for cellular proliferation. Overexpression of Plk1 is tightly associated with the development of certain cancers in humans, and a large body of evidence suggests that Plk1 is an attractive target for anticanc...

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Publicat a:Trends Pharmacol Sci
Autors principals: Lee, Kyung S., Burke, Terrence R., Park, Jung-Eun, Bang, Jeong K., Lee, Eunhye
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684765/
https://ncbi.nlm.nih.gov/pubmed/26478211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2015.08.013
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