Mist1 expressing gastric stem cells maintain the normal and neoplastic gastric epithelium and are supported by a perivascular stem cell niche

The regulation and stem cell origin of normal and neoplastic gastric glands are uncertain. Here, we show that Mist1 expression marks quiescent stem cells in the gastric corpus isthmus. Mist1(+) stem cells serve as a cell-of-origin for intestinal-type cancer with the combination of Kras and Apc mutat...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Cancer Cell
Autors principals: Hayakawa, Yoku, Ariyama, Hiroshi, Stancikova, Jitka, Sakitani, Kosuke, Asfaha, Samuel, Renz, Bernhard W., Dubeykovskaya, Zinaida A., Shibata, Wataru, Wang, Hongshan, Westphalen, Christoph B., Chen, Xiaowei, Takemoto, Yoshihiro, Kim, Woosook, Khurana, Shradha S., Tailor, Yagnesh, Nagar, Karan, Tomita, Hiroyuki, Hara, Akira, Sepulveda, Antonia R., Setlik, Wanda, Gershon, Michael D., Saha, Subhrajit, Ding, Lei, Shen, Zeli, Fox, James G., Friedman, Richard A., Konieczny, Stephen F., Worthley, Daniel L., Korinek, Vladimir, Wang, Timothy C.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684751/
https://ncbi.nlm.nih.gov/pubmed/26585400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2015.10.003
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars