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Functional and Structural Consequence of Rare Exonic Single Nucleotide Polymorphisms: One Story, Two Tales

Genetic variation arising from single nucleotide polymorphisms (SNPs) is ubiquitously found among human populations. While disease-causing variants are known in some cases, identifying functional or causative variants for most human diseases remains a challenging task. Rare SNPs, rather than common...

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Detalhes bibliográficos
Publicado no:Genome Biol Evol
Main Authors: Gu, Wanjun, Gurguis, Christopher I., Zhou, Jin J., Zhu, Yihua, Ko, Eun-A., Ko, Jae-Hong, Wang, Ting, Zhou, Tong
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684694/
https://ncbi.nlm.nih.gov/pubmed/26454016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evv191
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