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Non-Silent Story on Synonymous Sites in Voltage-Gated Ion Channel Genes

Synonymous mutations are usually referred to as “silent”, but increasing evidence shows that they are not neutral in a wide range of organisms. We looked into the relationship between synonymous codon usage bias and residue importance of voltage-gated ion channel proteins in mice, rats, and humans....

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Detalhes bibliográficos
Main Authors: Zhou, Tong, Ko, Eun A., Gu, Wanjun, Lim, Inja, Bang, Hyoweon, Ko, Jae-Hong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3485311/
https://ncbi.nlm.nih.gov/pubmed/23119053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048541
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