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Inflammatory targets of therapy in sickle cell disease

Sickle cell disease (SCD) is a monogenic globin disorder characterized by the production of a structurally abnormal hemoglobin (Hb) variant Hb S, which causes severe hemolytic anemia, episodic painful vaso-occlusion and ultimately end-organ damage. The primary disease pathophysiology is intracellula...

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Bibliografiske detaljer
Udgivet i:Transl Res
Main Authors: Owusu-Ansah, Amma, Ihunnah, Chibueze A., Walker, Aisha L., Ofori-Acquah, Solomon F.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684475/
https://ncbi.nlm.nih.gov/pubmed/26226206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trsl.2015.07.001
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