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Delayed Induction of Human NTE (PNPLA6) Rescues Neurodegeneration and Mobility Defects of Drosophila swiss cheese (sws) Mutants

Human PNPLA6 gene encodes Neuropathy Target Esterase protein (NTE). PNPLA6 gene mutations cause hereditary spastic paraplegia (SPG39 HSP), Gordon-Holmes syndrome, Boucher-Neuhäuser syndromes, Laurence-Moon syndrome, and Oliver-McFarlane syndrome. Mutations in the Drosophila NTE homolog swiss cheese...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Sujkowski, Alyson, Rainier, Shirley, Fink, John K., Wessells, Robert J.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684404/
https://ncbi.nlm.nih.gov/pubmed/26671664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145356
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