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Melatonin Activates Endoplasmic Reticulum Stress and Apoptosis in Rats with Diethylnitrosamine-Induced Hepatocarcinogenesis

Hepatocellular carcinoma (HCC) is one of the most lethal human cancers worldwide because of its high incidence, its metastatic potential and the low efficacy of conventional treatment. Inactivation of apoptosis is implicated in tumour progression and chemotherapy resistance, and has been linked to t...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Moreira, Andrea Janz, Ordoñez, Raquel, Cerski, Carlos Thadeu, Picada, Jaqueline Nascimento, García-Palomo, Andrés, Marroni, Norma Possa, Mauriz, Jose L., González-Gallego, Javier
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684373/
https://ncbi.nlm.nih.gov/pubmed/26656265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144517
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