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Oxidative stress and cell damage in a model of precancerous lesions and advanced hepatocellular carcinoma in rats

Hepatocellular carcinoma (HCC) is the third most frequent cause of cancer deaths throughout the world. This study was aimed to analyze oxidative stress and cell damage in a multistage model of liver carcinogenesis induced by diethylnitrosamine (DEN) in rats. Male Wistar rats weighing 145–150 g were...

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Detalhes bibliográficos
Publicado no:Toxicol Rep
Main Authors: Moreira, Andrea J., Rodrigues, Graziella, Bona, Silvia, Cerski, Carlos Thadeu, Marroni, Claudio A., Mauriz, Jose L., González-Gallego, Javier, Marroni, Norma P.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5598147/
https://ncbi.nlm.nih.gov/pubmed/28962366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxrep.2014.11.015
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