Atherosclerosis Susceptibility in Mice Is Independent of the V1 Immunoglobulin Heavy Chain Gene

The V1 (V(H)S107.1.42) immunoglobulin heavy chain gene is thought to be critical in producing IgM natural antibodies of the T15-idiotype that protect against both atherosclerosis and infection from Streptococcus pneumoniae. Our aim was to determine whether genetic loss of the V1 gene increased ather...

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Vydáno v:Arterioscler Thromb Vasc Biol
Hlavní autoři: Centa, Monica, Gruber, Sabrina, Nilsson, Daniel, Polyzos, Konstantinos A., Johansson, Daniel K., Hansson, Göran K., Ketelhuth, Daniel F.J., Binder, Christoph J., Malin, Stephen
Médium: Artigo
Jazyk:Inglês
Vydáno: Lippincott Williams & Wilkins 2016
Témata:
Basic Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684249/
https://ncbi.nlm.nih.gov/pubmed/26564818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.115.305990
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