Erythroid-Specific Expression of LIN28A Is Sufficient for Robust Gamma-Globin Gene and Protein Expression in Adult Erythroblasts

Increasing fetal hemoglobin (HbF) levels in adult humans remains an active area in hematologic research. Here we explored erythroid-specific LIN28A expression for its effect in regulating gamma-globin gene expression and HbF levels in cultured adult erythroblasts. For this purpose, lentiviral transd...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Lee, Y. Terry, de Vasconcellos, Jaira F., Byrnes, Colleen, Kaushal, Megha, Rabel, Antoinette, Tumburu, Laxminath, Allwardt, Joshua M., Miller, Jeffery L.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684222/
https://ncbi.nlm.nih.gov/pubmed/26675483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144977
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker