Loss of GATA-1 Full Length as a Cause of Diamond–Blackfan Anemia Phenotype

Mutations in the hematopoietic transcription factor GATA-1 alter the proliferation/differentiation of hemopoietic progenitors. Mutations in exon 2 interfere with the synthesis of the full-length isoform of GATA-1 and lead to the production of a shortened isoform, GATA-1s. These mutations have been f...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Pediatr Blood Cancer
Main Authors: Parrella, Sara, Aspesi, Anna, Quarello, Paola, Garelli, Emanuela, Pavesi, Elisa, Carando, Adriana, Nardi, Margherita, Ellis, Steven R., Ramenghi, Ugo, Dianzani, Irma
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684094/
https://ncbi.nlm.nih.gov/pubmed/24453067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.24944
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker