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Increased toxin expression in a Clostridium difficile mfd mutant

BACKGROUND: The symptoms of Clostridium difficile infection are mediated primarily by two toxins, TcdA and TcdB, the expression of which is governed by a multitude of factors including nutrient availability, growth phase and cell stress. Several global regulators have been implicated in the regulati...

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Detalhes bibliográficos
Publicado no:BMC Microbiol
Main Authors: Willing, Stephanie E., Richards, Emma J., Sempere, Lluis, Dale, Aaron G., Cutting, Simon M., Fairweather, Neil F.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4683965/
https://ncbi.nlm.nih.gov/pubmed/26679502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12866-015-0611-5
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