Sleeping Beauty Transposon Mutagenesis as a Tool for Gene Discovery in the NOD Mouse Model of Type 1 Diabetes

A number of different strategies have been used to identify genes for which genetic variation contributes to type 1 diabetes (T1D) pathogenesis. Genetic studies in humans have identified >40 loci that affect the risk for developing T1D, but the underlying causative alleles are often difficult to...

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Библиографические подробности
Опубликовано в: :G3 (Bethesda)
Главные авторы: Elso, Colleen M., Chu, Edward P. F., Alsayb, May A., Mackin, Leanne, Ivory, Sean T., Ashton, Michelle P., Bröer, Stefan, Silveira, Pablo A., Brodnicki, Thomas C.
Формат: Artigo
Язык:Inglês
Опубликовано: Genetics Society of America 2015
Предметы:
Mutant Screen Report
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4683661/
https://ncbi.nlm.nih.gov/pubmed/26438296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.115.021709
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