Cysteines 208 and 241 in Ero1α are required for maximal catalytic turnover

Endoplasmic reticulum (ER) oxidoreductin 1α (Ero1α) is a disulfide producer in the ER of mammalian cells. Besides four catalytic cysteines (Cys(94), Cys(99), Cys(394), Cys(397)), Ero1α harbors four regulatory cysteines (Cys(104), Cys(131), Cys(208), Cys(241)). These cysteines mediate the formation o...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Redox Biol
Egile Nagusiak: Ramming, Thomas, Kanemura, Shingo, Okumura, Masaki, Inaba, Kenji, Appenzeller-Herzog, Christian
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2015
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4683387/
https://ncbi.nlm.nih.gov/pubmed/26609561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2015.11.004
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