Xenotransplantation of Human Cardiomyocyte Progenitor Cells Does Not Improve Cardiac Function in a Porcine Model of Chronic Ischemic Heart Failure. Results from a Randomized, Blinded, Placebo Controlled Trial

BACKGROUND: Recently cardiomyocyte progenitor cells (CMPCs) were successfully isolated from fetal and adult human hearts. Direct intramyocardial injection of human CMPCs (hCMPCs) in experimental mouse models of acute myocardial infarction significantly improved cardiac function compared to controls....

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Jansen of Lorkeers, Sanne J., Gho, Johannes M. I. H., Koudstaal, Stefan, van Hout, Gerardus P. J., Zwetsloot, Peter Paul M., van Oorschot, Joep W. M., van Eeuwijk, Esther C. M., Leiner, Tim, Hoefer, Imo E., Goumans, Marie-José, Doevendans, Pieter A., Sluijter, Joost P. G., Chamuleau, Steven A. J.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4683045/
https://ncbi.nlm.nih.gov/pubmed/26678993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143953
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