Xenotransplantation of Human Cardiomyocyte Progenitor Cells Does Not Improve Cardiac Function in a Porcine Model of Chronic Ischemic Heart Failure. Results from a Randomized, Blinded, Placebo Controlled Trial

BACKGROUND: Recently cardiomyocyte progenitor cells (CMPCs) were successfully isolated from fetal and adult human hearts. Direct intramyocardial injection of human CMPCs (hCMPCs) in experimental mouse models of acute myocardial infarction significantly improved cardiac function compared to controls....

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Vydáno v:PLoS One
Hlavní autoři: Jansen of Lorkeers, Sanne J., Gho, Johannes M. I. H., Koudstaal, Stefan, van Hout, Gerardus P. J., Zwetsloot, Peter Paul M., van Oorschot, Joep W. M., van Eeuwijk, Esther C. M., Leiner, Tim, Hoefer, Imo E., Goumans, Marie-José, Doevendans, Pieter A., Sluijter, Joost P. G., Chamuleau, Steven A. J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4683045/
https://ncbi.nlm.nih.gov/pubmed/26678993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143953
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