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Influence of Glycosylation Inhibition on the Binding of KIR3DL1 to HLA-B*57:01

Viral infections can affect the glycosylation pattern of glycoproteins involved in antiviral immunity. Given the importance of protein glycosylation for immune function, we investigated the effect that modulation of the highly conserved HLA class I N-glycan has on KIR:HLA interactions and NK cell fu...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Salzberger, Wilhelm, Garcia-Beltran, Wilfredo F., Dugan, Haley, Gubbala, Supreetha, Simoneau, Camille, Gressens, Simon B., Jost, Stephanie, Altfeld, Marcus
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4683028/
https://ncbi.nlm.nih.gov/pubmed/26680341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145324
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