A Novel Bispecific Antibody against Human CD3 and Ephrin Receptor A10 for Breast Cancer Therapy

Ephrin receptor A10 (EphA10), a transmembrane receptor that binds to ephrin, is a newly identified breast cancer marker protein that has also been detected in HER2-negative tissue. In this study, we report creation of a novel bispecific antibody (BsAb) binding both EphA10 and CD3, thereby forming a...

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Udgivet i:PLoS One
Main Authors: Taki, Shintaro, Kamada, Haruhiko, Inoue, Masaki, Nagano, Kazuya, Mukai, Yohei, Higashisaka, Kazuma, Yoshioka, Yasuo, Tsutsumi, Yasuo, Tsunoda, Shin-ichi
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4682974/
https://ncbi.nlm.nih.gov/pubmed/26678395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144712
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