The Hepatitis B Virus Genotype Affects the Persistence of Viral Replication in Immunodeficient NOG Mice

BACKGROUND & AIMS: At least eight genotypes of Hepatitis B virus (HBV) have been identified. HBV genotype C is the most common genotype in Japan, although the incidence of HBV genotype A is increasing. The reason underlying the differences in viral multiplication of the HBV genotypes is unclear,...

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Publicat a:PLoS One
Autors principals: Yokoyama, Yoshinobu, Miyagi, Takuya, Hikita, Hayato, Yoshioka, Teppei, Mukai, Kaori, Nawa, Takatoshi, Sakamori, Ryotaro, Ohkawa, Kazuyoshi, Hiramatsu, Naoki, Takahashi, Takeshi, Suemizu, Hiroshi, Ryo, Akihide, Tatsumi, Tomohide, Takehara, Tetsuo
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4682774/
https://ncbi.nlm.nih.gov/pubmed/26658490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144775
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