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Adeno-Associated Virus Mediated Delivery of An Engineered Protein that Combines the Complement Inhibitory Properties of CD46, CD55 and CD59

BACKGROUND: A variety of disorders are associated with the activation of complement. CD46, CD55 and CD59 are the major membrane associated regulators of complement on human cells. Previously, we have found that independent expression of CD55, CD46 or CD59 through gene transfer protects murine tissue...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Gene Med
Main Authors: Leaderer, Derek, Cashman, Siobhan M., Kumar-Singh, Rajendra
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4682684/
https://ncbi.nlm.nih.gov/pubmed/25917932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jgm.2829
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