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Adeno-Associated Virus Mediated Delivery of An Engineered Protein that Combines the Complement Inhibitory Properties of CD46, CD55 and CD59

BACKGROUND: A variety of disorders are associated with the activation of complement. CD46, CD55 and CD59 are the major membrane associated regulators of complement on human cells. Previously, we have found that independent expression of CD55, CD46 or CD59 through gene transfer protects murine tissue...

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Detalhes bibliográficos
Publicado no:J Gene Med
Main Authors: Leaderer, Derek, Cashman, Siobhan M., Kumar-Singh, Rajendra
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4682684/
https://ncbi.nlm.nih.gov/pubmed/25917932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jgm.2829
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