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Subcritical Water Hydrolysis Effectively Reduces the In Vitro Seeding Activity of PrP(Sc) but Fails to Inactivate the Infectivity of Bovine Spongiform Encephalopathy Prions

The global outbreak of bovine spongiform encephalopathy (BSE) has been attributed to the recycling of contaminated meat and bone meals (MBMs) as feed supplements. The use of MBMs has been prohibited in many countries; however, the development of a method for inactivating BSE prions could enable the...

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Vydáno v:PLoS One
Hlavní autoři: Murayama, Yuichi, Yoshioka, Miyako, Okada, Hiroyuki, Takata, Eri, Masujin, Kentaro, Iwamaru, Yoshifumi, Shimozaki, Noriko, Yamamura, Tomoaki, Yokoyama, Takashi, Mohri, Shirou, Tsutsumi, Yuji
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4682654/
https://ncbi.nlm.nih.gov/pubmed/26675475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144761
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