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Neutrophil Elastase-Generated Fragment of Vascular Endothelial Growth Factor-A Stimulates Macrophage and Endothelial Progenitor Cell Migration

Elastase released from neutrophils as part of the innate immune system has been implicated in chronic diseases such as emphysema and cardiovascular disease. We have previously shown that neutrophil elastase targets vascular endothelial growth factor-A (VEGF) for partial degradation to generate a fra...

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Publicat a:PLoS One
Autors principals: Kurtagic, Elma, Rich, Celeste B., Buczek-Thomas, Jo Ann, Nugent, Matthew A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4682631/
https://ncbi.nlm.nih.gov/pubmed/26672607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145115
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