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Neutrophil elastase cleaves VEGF to generate a VEGF fragment with altered activity

Excessive neutrophil elastase (NE) activity and altered vascular endothelial growth factor (VEGF) signaling have independently been implicated in the development and progression of pulmonary emphysema. In the present study, we investigated the potential link between NE and VEGF. We noted that VEGF(1...

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Sonraí Bibleagrafaíochta
Main Authors: Kurtagic, Elma, Jedrychowski, Mark P., Nugent, Matthew A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Physiological Society 2009
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660218/
https://ncbi.nlm.nih.gov/pubmed/19136576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90505.2008
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