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PHLPP2 Downregulation Contributes to Lung Carcinogenesis Following B[a]P/B[a]PDE Exposure

PURPOSE: The carcinogenic capacity of B[a]P/B[a]PDE is supported by epidemiologic studies. However, the molecular mechanisms responsible for B[a]P/B[a]PDE-caused lung cancer have not been well investigated. We evaluated here the role of novel target PHLPP2 in lung inflammation and carcinogenesis upo...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Huang, Haishan, Pan, Xiaofu, Jin, Honglei, Li, Yang, Zhang, Lin, Yang, Caili, Liu, Pei, Liu, Ya, Chen, Lili, Li, Jingxia, Zhu, Junlan, Zeng, Xingruo, Fu, Kai, Chen, Guorong, Gao, Jimin, Huang, Chuanshu
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4682561/
https://ncbi.nlm.nih.gov/pubmed/25977341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-2829
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