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A systematic analysis of a broadly neutralizing antibody AR3C epitopes on Hepatitis C virus E2 envelope glycoprotein and their cross-reactivity

BACKGROUND: Hepatitis C virus (HCV) belongs to Flaviviridae family of viruses. HCV represents a major challenge to public health since its estimated global prevalence is 2.8% of the world's human population. The design and development of HCV vaccine has been hampered by rapid evolution of viral...

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Detalhes bibliográficos
Publicado no:BMC Med Genomics
Main Authors: Sun, Jing, Brusic, Vladimir
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4682370/
https://ncbi.nlm.nih.gov/pubmed/26681161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-8-S4-S6
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