Non-genetic Purification of Ventricular Cardiomyocytes from Differentiating Embryonic Stem Cells through Molecular Beacons Targeting IRX-4

Isolation of ventricular cardiomyocytes (vCMs) has been challenging due to the lack of specific surface markers. Here we show that vCMs can be purified from differentiating mouse embryonic stem cells (mESCs) using molecular beacons (MBs) targeting specific intracellular mRNAs. We designed MBs (IRX4...

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Bibliographic Details
Published in:Stem Cell Reports
Main Authors: Ban, Kiwon, Wile, Brian, Cho, Kyu-Won, Kim, Sangsung, Song, Ming-Ke, Kim, Sang Yoon, Singer, Jason, Syed, Anum, Yu, Shan Ping, Wagner, Mary, Bao, Gang, Yoon, Young-sup
Format: Artigo
Language:Inglês
Published: Elsevier 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4682289/
https://ncbi.nlm.nih.gov/pubmed/26651608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2015.10.021
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