Decreased PCSK9 expression in human hepatocellular carcinoma

BACKGROUND: The management of hepatocellular carcinoma (HCC) is limited by the lack of adequate screening biomarkers and chemotherapy. In response, there has been much interest in tumor metabolism as a therapeutic target. PCSK9 stimulates internalization of the LDL-receptor, decreases cholesterol up...

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Detalhes bibliográficos
Publicado no:BMC Gastroenterol
Main Authors: Bhat, Mamatha, Skill, Nicolas, Marcus, Victoria, Deschenes, Marc, Tan, Xianming, Bouteaud, Jeanne, Negi, Sarita, Awan, Zuhier, Aikin, Reid, Kwan, Janet, Amre, Ramila, Tabaries, Sebastien, Hassanain, Mazen, Seidah, Nabil G., Maluccio, Mary, Siegel, Peter, Metrakos, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4682218/
https://ncbi.nlm.nih.gov/pubmed/26674961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12876-015-0371-6
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