Metformin Acts on Two Different Molecular Pathways to Enhance Adult Neural Precursor Proliferation/Self-Renewal and Differentiation

The recruitment of endogenous adult neural stem cells for brain repair is a promising regenerative therapeutic strategy. This strategy involves stimulation of multiple stages of adult neural stem cell development, including proliferation, self-renewal, and differentiation. Currently, there is a lack...

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Bibliographische Detailangaben
Veröffentlicht in:Stem Cell Reports
Hauptverfasser: Fatt, Michael, Hsu, Karolynn, He, Ling, Wondisford, Fredric, Miller, Freda D., Kaplan, David R., Wang, Jing
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2015
Schlagworte:
Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4682208/
https://ncbi.nlm.nih.gov/pubmed/26677765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2015.10.014
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