Autophagic degradation of aquaporin-2 is an early event in hypokalemia-induced nephrogenic diabetes insipidus

Hypokalemia (low serum potassium level) is a common electrolyte imbalance that can cause a defect in urinary concentrating ability, i.e., nephrogenic diabetes insipidus (NDI), but the molecular mechanism is unknown. We employed proteomic analysis of inner medullary collecting ducts (IMCD) from rats...

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Udgivet i:Sci Rep
Main Authors: Khositseth, Sookkasem, Uawithya, Panapat, Somparn, Poorichaya, Charngkaew, Komgrid, Thippamom, Nattakan, Hoffert, Jason D., Saeed, Fahad, Michael Payne, D., Chen, Shu-Hui, Fenton, Robert A., Pisitkun, Trairak
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4682130/
https://ncbi.nlm.nih.gov/pubmed/26674602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18311
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