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The aglycone of ginsenoside Rg3 enables glucagon-like peptide-1 secretion in enteroendocrine cells and alleviates hyperglycemia in type 2 diabetic mice

Ginsenosides can be classified on the basis of the skeleton of their aglycones. Here, we hypothesized that the sugar moieties attached to the dammarane backbone enable binding of the ginsenosides to the sweet taste receptor, eliciting glucagon-like peptide-1 (GLP-1) secretion in the enteroendocrine...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kim, Ki-Suk, Jung Yang, Hea, Lee, In-Seung, Kim, Kang-Hoon, Park, Jiyoung, Jeong, Hyeon-Soo, Kim, Yoomi, Seok Ahn, Kwang, Na, Yun-Cheol, Jang, Hyeung-Jin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4682129/
https://ncbi.nlm.nih.gov/pubmed/26675132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18325
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